The HDRCOE seeks to eliminate health disparities, promote health equity, inform public policy, and transform public health practice through the advancement of team science and the application of computational methods, geographic information systems, and spatial temporal analysis through an exposome lens.

The exposome considers the mechanisms and pathways through which the natural, built, social and policy environments affect personal health outcomes and population level disparities across space, time and the life course.



To use an innovative, transdisciplinary, total exposome approach and multi-level and multi-dimensional analytics and modeling to move the research community closer towards identifying both causal mechanisms and pathways and mediating and moderating factors underlying disease and population level disparities. We seek to identify cumulative risks and model completeexposure pathways associated with diseases and conditions that disproportionately impact racial/ethnic and other vulnerable populations.



The Center will demonstrate a measurable impact on addressing minority health and racial/ethnic disparities in health disparities through the following aims:

  1. Apply a systems science approach and trans-disciplinary methodological tools, models, and analytics to better understand the relationships between biological and environmental factors contributing to poor health outcomes and population-level disparities.
  2. Identify mechanisms and pathways of chemical and non-chemical, exposures associated with healthy and unhealthy disease outcomes among health disparities populations.
  3. Contribute to the expansion of a diverse research workforce trained in transdisciplinary team science for conducting minority health and health disparities research.
  4. Coordinate translation and dissemination activities with the scientific community, public health care providers, primary care clinicians, community members, and policymakers.
  5. Evaluate overall progress of the Center, its research projects and training activities.